SCIENTIFIC WORK

Publications

Selected scientific publications from the Boztug Laboratory and our collaborators across human immunology, genetics, immune dysregulation and inborn errors of immunity.

RESEARCH OUTPUT

Selected Publications

PAPER2026
2026Nature

Host control of persistent Epstein-Barr virus infection.

Schmidt A, Alawathurage TM, David FS, Ogawa Y, Frach L, Richter S, Schaefer M, Mathey CM, Henne SK; Japan COVID-19 Task Force; Forstner AJ, Dilthey AT, Pröbstel AK, Boztug K, Nöthen MM, Namkoong H, Okada Y, Beins EC, Ludwig KU.

Nature. 2026 May;653(8114):444-454. Epub 2026 Feb 19.

DOI: 10.1038/s41586-026-10274-4

PMID: 41714741

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PAPER2025
2025Science Immunology

Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes.

Kalinichenko A, Huemer J, Humer T, Haimel M, Svaton M, Socquet-Juglard N, Casoni GP, Prakash C, von der Linde M, Pazmandi J, van de Wetering C, Nunez-Fontarnau J, Kamnev A, Giuliani S, Jaeger MG, Hahn E, Dobner S, Rukavina A, Sylvander E, Seigner J, Rashkova C, Hoeger B, Traxlmayr MW, Lehner M, Bryceson YT, Saarela J, Hannich T, Castanon I, Winter G, Dupré L, Boztug K.

Science Immunology. 2025 Oct 17;10(112):eado3825.

DOI: 10.1126/sciimmunol.ado3825

PMID: 41105755

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PAPER2025
2025Nature Reviews Immunology

Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation.

Dupré L, Castanon I, Boztug K.

Nature Reviews Immunology. 2026 Feb;26(2):89-111. Epub 2025 Sep 10.

DOI: 10.1038/s41577-025-01214-w

PMID: 40931027

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PAPER2025
2025Cell Reports Medicine

Image-based drug screening combined with molecular profiling identifies signatures and drivers of therapy resistance in pediatric AML.

Haladik B, Maurer-Granofszky M, Zoescher P, Jimenez-Heredia R, Frohne A, Segarra-Roca A, Casey C, Kartnig F, Giuliani S, Rashkova C, Repiscak P, Dworzak MN, Superti-Furga G, Boztug K.

Cell Reports Medicine. 2025 Sep 16;6(9):102304. Epub 2025 Aug 20.

DOI: 10.1016/j.xcrm.2025.102304

PMID: 40840446

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RESEARCH AREAS

Our scientific focus

01

Monogenic
Actinopathies

02

Monogenic HLH

03

Monogenic
Inflammatory
Bowel Disease